Prof. Dr. med. Mario Perl, MHBA

Unsere Publikationen zum Fachgebiet Trauma-Immunologie

1. Weber B, Lackner I, Gebhard F, Miclau T, Kalbitz M. Trauma, a Matter of the Heart-Molecular Mechanism of Post-Traumatic Cardiac Dysfunction. Int J Mol Sci. 2021;22(2).

2. Weber B, Lackner I, Baur M, Gebhard F, Pfeifer R, Cinelli P, Halvachizadeh S, Teuben M, Pape HC, Imhof A, Lipiski M, Cesarovic N, Kalbitz M. Early myocardial damage (EMD) and valvular insufficiency result in impaired cardiac function after multiple trauma in pigs. Sci Rep. 2021;11(1):1151.

3. Kalbitz M, Weber B, Lackner I, Beer M, Pressmar J. Olecranon fractures in children: treatment of a rare entity. Eur J Trauma Emerg Surg. 2020. PMID: 33231705

4. Lackner I, Weber B, Miclau T, Holzwarth N, Baur M, Gebhard F, Teuben M, Halvachizadeh S, Cinelli P, Pfeifer R, Lipiski M, Cesarovic N, Haffner-Luntzer M, Pape HC, Kalbitz M. Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma. J Orthop Res. 2020;38(12):2608-18.

5. Baur M, Weber B, Lackner I, Gebhard F, Pfeifer R, Cinelli P, Halvachizadeh S, Teuben M, Lipiski M, Cesarovic N, Pape HC, Kalbitz M. Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing. PLoS One. 2020;15(6):e0235220.

6. Lackner I, Weber B, Chakraborty S, Braumuller S, Huber-Lang M, Gebhard F, Kalbitz M. Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis. Mediators of Inflammation. 2020;2020:12.

7. Weber B, Lackner I, Baur M, Fois G, Gebhard F, Marzi I, Schrezenmeier H, Relja B, Kalbitz M. Effects of Circulating HMGB-1 and Histones on Cardiomyocytes-Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma. Journal of clinical medicine. 2020;9(5).

8. Pressmar J, Weber B, Kalbitz M. Different classifications concerning fractures of the lateral humeral condyle in children. European journal of trauma and emergency surgery : official publication of the European Trauma Society. 2020.

9. Weber B, Lackner I, Knecht D, Braun CK, Gebhard F, Huber-Lang M, Hildebrand F, Horst K, Pape HC, Ignatius A, Schrezenmeier H, Haffner-Luntzer M, Kalbitz M. Systemic and Cardiac Alterations After Long Bone Fracture. Shock. 2020.

10. Halbgebauer R, Kellermann S, Schäfer F, Weckbach S, Weiss M, Barth E, Bracht H, Kalbitz M, Gebhard F, Huber-Lang MS, Perl M. Functional immune monitoring in severely injured patients-A pilot study. Scand J Immunol. 2020 Feb;91(2):e12837.

11. Lackner I, Weber B, Baur M, Fois G, Gebhard F, Pfeifer R, Cinelli P, Halvachizadeh S, Lipiski M, Cesarovic N, Schrezenmeier H, Huber-Lang M, Pape H-C, Kalbitz M. Complement Activation and Organ Damage After Trauma—Differential Immune Response Based on Surgical Treatment Strategy. Frontiers in immunology. 2020;11(64).

12. Lackner I, Weber B, Baur M, Haffner-Luntzer M, Eiseler T, Fois G, Gebhard F, Relja B, Marzi I, Pfeifer R, Halvachizadeh S, Lipiski M, Cesarovic N, Pape HC, Kalbitz M. Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism. Frontiers in immunology. 2019;10:1920.

13. Wagner N, Dieteren S, Franz N, Köhler K, Perl M, Marzi I, Relja B. Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage. Int J Mol Med. 2019 Sep;44(3):1127-1138.

14. Weber B, Lackner I, Haffner-Luntzer M, Palmer A, Pressmar J, Scharffetter-Kochanek K, Knoll B, Schrezenemeier H, Relja B, Kalbitz M. Modeling trauma in rats: similarities to humans and potential pitfalls to consider. Journal of translational medicine. 2019;17(1):305.

15. Weber B, Mendler MR, Lackner I, Pressmar J, Haffner-Luntzer M, Hofler S, Braun CK, Hummler H, Schwarz S, Kalbitz M. Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs. Pediatric research. 2019;86(6):709-18.

16. Lackner I, Weber B, Knecht D, Horst K, Relja B, Gebhard F, Pape HC, Huber-Lang M, Hildebrand F, Kalbitz M. Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma. Shock. 2019.

17. Weber B, Mendler MR, Lackner I, von Zelewski A, Höfler S, Baur M, Braun CK, Hummler H, Schwarz S, Pressmar J, Kalbitz M. Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes. PLoS One. 2019;14(7):e0219211.

18. Foertsch S, Lackner I, Weber B, Fuchsl AM, Langgartner D, Wirkert E, Peters S, Fois G, Pressmar J, Fegert JM, Frick M, Gundel H, Kalbitz M*, Reber SO*. Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma. Brain, behavior, and immunity. 2019.

19. Fischer V*, Kalbitz M*, Muller-Graf F, Gebhard F, Ignatius A, Liedert A, Haffner-Luntzer M. Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing. Int J Mol Sci. 2018;19(7).

20. Kalbitz M, Schwarz S, Weber B, Bosch B, Pressmar J, Hoenes FM, Braun CK, Horst K, Simon TP, Pfeifer R, Stormann P, Hummler H, Gebhard F, Pape HC, Huber-Lang M, Hildebrand F. Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations. Sci Rep. 2017;7(1):17861.

21. Kalbitz M, Amann EM, Bosch B, Palmer A, Schultze A, Pressmar J, Weber B, Wepler M, Gebhard F, Schrezenmeier H, Brenner R, Huber-Lang M. Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43. PLoS One. 2017;12(11):e0187270.

22. Kalbitz M, Waller C, Huber-Lang M, Gebhard F, Thiemermann C, Radermacher P. Oxygen in the Heart: How Much is too Much? Shock. 2017;47(4):531-2.

23. Kalbitz M, Fattahi F, Grailer JJ, Jajou L, Malan EA, Zetoune FS, Huber-Lang M, Russell MW, Ward PA. Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2016;30(12):3997-4006.

24. Kalbitz M, Fattahi F, Herron TJ, Grailer JJ, Jajou L, Lu H, Huber-Lang M, Zetoune FS, Sarma JV, Day SM, Russell MW, Jalife J, Ward PA. Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro. Journal of immunology (Baltimore, Md : 1950). 2016;197(6):2353-61.

25. Kalbitz M, Pressmar J, Stecher J, Weber B, Weiss M, Schwarz S, Miltner E, Gebhard F, Huber-Lang M. The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans. World J Surg. 2017;41(1):162-9.

26. Kalbitz M, Karbach M, Braumueller S, Kellermann P, Gebhard F, Huber-Lang M, Perl M. Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI). PLoS One. 2016;11(7):e0159417.

27. Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015;29(5):2185-93.

28. Weber B, Lackner I, Miclau T, Stulz J, Gebhard F, Pfeifer R, Cinelli P, Halvachizadeh S, Teuben M, Pape HC, Lipiski M, Cesarovic N, Kalbitz M. Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs. Sci Rep. 2021 Apr 19;11(1):8503.

29. Weber B, Lackner I, Braun CK, Kalbitz M, Huber-Lang M, Pressmar J. Laboratory Markers in the Management of Pediatric Polytrauma: Current Role and Areas of Future Research.Front Pediatr. 2021 Mar 16;9:622753.

30. Luntzer K, Lackner I, Weber B, Mödinger Y, Ignatius A, Gebhard F, Mihaljevic SY, Haffner-Luntzer M, Kalbitz M.Increased Presence of Complement Factors and Mast Cells in Alveolar Bone and Tooth Resorption. Int J Mol Sci. 2021 Mar 9;22(5):2759.

31. . Weber B, Kalbitz M, Baur M, Braun CK, Zwingmann J, Pressmar J. Lower Leg Fractures in Children and Adolescents-Comparison of Conservative vs. ECMES Treatment. Front Pediatr. 2021 Mar 4;9:597870. 

32.. Lackner I, Weber B, Haffner-Luntzer M, Hristova S, Gebhard F, Lam C, Morioka K, Marcucio RS, Miclau T, Kalbitz M.Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice.J Orthop Translat. 2021 Feb 23;28:39-46.

Prof. Dr. med. Miriam Kalbitz
Dr. rer. nat. Ina Lackner
Prof. Dr. med. Mario Perl , MHBA